Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) - Game-Changers in Dentistry
​
Tooth loss is a common issue worldwide. According to the American College of Prosthodontists, more than 187 million American adults have lost at least one tooth — and nearly 30% of adults aged 65–74 have lost all of their teeth.
​
Why Dental Implants Are the Gold Standard
When replacing missing teeth, dental implants are the most trusted solution. They are durable, look natural, and restore full chewing function. For implants to succeed, they must fuse with the jawbone in a process called osseointegration. The stronger and healthier the bone around the implant, the more stable and long-lasting the result.
At Harsono Dental, we use advanced, proven techniques to improve implant success. Two of the most exciting innovations are platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) — therapies that use your own blood to naturally speed healing and boost bone growth.
What is PRP?
Platelet-Rich Plasma (PRP) is made by drawing a small sample of your blood and separating out the platelets — cells that help with clotting and healing. These platelets are packed with growth factors, which can stimulate tissue repair and bone regeneration. When placed at a surgical site, PRP encourages faster recovery.
What is PRF?
Platelet-Rich Fibrin (PRF) is a newer, natural form of platelet concentrate. Like PRP, it’s made from your own blood — but without any additives or chemicals. Using a special centrifuge, we create a soft clot that contains platelets, white blood cells, and fibrin fibers.
PRF has been widely used in dentistry for over 20 years and is especially valuable in dental implant surgery, where it helps reduce inflammation, fight infection, and promote long-term bone and gum healing.
​
PRP vs. PRF: What’s the Difference?
Both PRP and PRF accelerate healing, but there are key differences:
-
Preparation
-
PRP requires an anti-coagulant and high-speed centrifuge.
-
PRF uses no chemicals and is spun at a lower speed.
-
-
Release of Growth Factors
-
PRP releases growth factors quickly for an immediate effect.
-
PRF releases them slowly, providing a steady, long-term healing boost.
-
-
Scaffolding Effect
-
PRF creates a natural fibrin “matrix” that supports bone and tissue growth.
-
Why PRF is Often Preferred
While both PRP and PRF can be helpful, PRF is most commonly used for dental implants because of its sustained healing benefits. Many dentists consider it a “biological bandage.”
Benefits of PRF in Implant Dentistry:
-
Faster healing – growth factors are released gradually, helping tissues recover smoothly.
-
Better bone formation – platelets, fibrin, and white blood cells work together to support bone growth and implant stability.
-
Reduced inflammation – PRF naturally calms swelling and discomfort.
-
Lower infection risk – white blood cells in PRF enhance your body’s defenses.
-
No additives – safe, natural, and chemical-free.
How PRF is Made and Used
Making PRF is quick and safe:
-
A small blood sample is taken (like a routine test).
-
The blood is spun in a centrifuge to separate out the PRF clot.
-
The PRF is placed directly into the implant site, mixed with a bone graft if needed, or even used to coat the implant itself.
-
A PRF layer may also be applied as a “bandage” to protect and speed up healing.
What the Research Shows
Recent studies confirm PRF’s effectiveness:
-
A 2024 clinical study found that patients treated with PRF had stronger implant stability and better healing six months after surgery.
-
A 2023 meta-analysis (Heliyon journal) concluded that PRF significantly improved implant anchorage and accelerated bone healing.